Endocrine/Growth Hormone

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The clinical experience of GH in adults with PWS is not very well studied, but the first reports are encouraging. Two previous studies have suggested there are benefits to GH therapy in adults with respect body composition and physical performance [ Read more . . . ]

  Parents of newly diagnosed infants with PWS often wonder at what age to start growth hormone (GH) therapy. Advice from medical professionals is sometimes inconsistent, with some doctors advocating the use of GH as soon as possible after the diagnosis, while others prefer to wait until the baby/toddler starts to fall off his or her growth curve. [ Read more . . . ]

Dr. Phillip Lee is an expert on PWS endocrine issues; notably growth hormone therapy in PWS. He has recently written a review on the subject in the Growth, Genetics & Hormones journal, an online resource directed to endocrinologists and health professionals that reviews and comments on recent advances in the area of human growth. [ Read more . . . ]

Growth, Genetics, and Hormones is a free e-newsletter, primarily for endocrinologists (but anyone can sign up and receive it). One very nice feature they have is a review of recent articles of interest in the literature, with editorial comments about the implications of the studies. [ Read more . . . ]

There's a new paper out in a top journal, Science, on what is may be the first understanding of the underlying molecular basis of features of PWS - The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C -- I've put the link at the end of the message. Here's the lowdown: [ Read more . . . ]