Prader-Willi Syndrome (PWS) is a genetic disease characterized by failure to thrive and low muscle tone during infancy, followed by food-seeking and severe obesity in childhood. Other manifestations include altered pain perception, cognitive impairment, maladaptive behaviors (obsessive compulsive, temper tantrums, skin picking, rigid thinking and repetitive speech) and language difficulties. These maladaptive behaviors may be related to deficits in executive function.
Institution:
University of Alberta, Canada
