Recent research out of Italy, reported in the Journal of Clinical Endocrinology and Metabolism, highlights the potential benefits of long-term growth hormone (GH) therapy in adults with PWS. The study, involving 15 obese adults with PWS treated with GH over 2-years, showed improved body composition, muscle size and quality, and increased muscle strength and exercise tolerance. Interestingly, only 40% of the subjects had a growth hormone deficiency, indicating that even those individuals with relatively normal levels of GH may realize benefits from GH therapy. Understanding the benefits and risks of GH therapy in adults with PWS is an important next step in further developing standards of care for GH therapy.You may view the most recent
Growth Hormone Consensus Guidelines here. View the original paper here.