Long Term GH Therapy Improved Body Composition

Recent research out of Italy, reported in the Journal of Clinical Endocrinology and Metabolism, highlights the potential benefits of long-term growth hormone (GH) therapy in adults with PWS. The study, involving 15 obese adults with PWS treated with GH over 2-years, showed improved body composition, muscle size and quality, and increased muscle strength and exercise tolerance. Interestingly, only 40% of the subjects had a growth hormone deficiency, indicating that even those individuals with relatively normal levels of GH may realize benefits from GH therapy. Understanding the benefits and risks of GH therapy in adults with PWS is an important next step in further developing standards of care for GH therapy.You may view the most recent 
Growth Hormone Consensus Guidelines here. View the original paper here.

Topics: Research

Susan Hedstrom

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Susan Hedstrom is the Executive Director for the Foundation for Prader-Willi Research. Passionate about finding treatments for PWS, Susan joined FPWR in 2009 shortly after her son, Jayden, was diagnosed with Prader-Willi Syndrome. Rather than accepting PWS as it has been defined, Susan has chosen to work with a team of pro-active and tireless individuals to accelerate PWS research in order to change the natural history of PWS. Inspired by her first FPWR conference and the team of researchers that were working to find answers for the syndrome, she hosted her first One SMALL Step walk in 2010 and began the development of the One SMALL Step walk program which now raises over $1.5 million a year for PWS research.

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