Projects

Under the guidance of our Scientific Advisory Board through a carefully managed grants process, FPWR selects research projects based on the collaborative input of researchers and parents, choosing projects that are both scientifically meritorious and highly relevant for individuals with PWS and their families.

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Identifying novel SNORD116 targets and signaling pathways

Funded Year: 2025

A cluster of small nucleolar RNAs (snoRNAs), known as the SNORD116 cluster, appears to be of critical importance in Prader-Willi syndrome (PWS). However, despite over two decades of extensive investigation, a direct interaction between SNORD116 and a predicted target has yet to be shown, and as such the mechanism behind PWS remains unknown. Our...

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