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The Oxytocin Landscape

The science of oxytocin (OT) and its potential therapeutic benefit in PWS continues to be a high profile, priority research area for the PWS community and for FPWR. Several studies have taken place investigating oxytocin as a therapeutic for PWS, however, there is still much more we need to know. There is a lot going […]

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Optogenetics: a new research tool in understanding the neurobiology underlying PWS behaviors

It’s likely that improper development and/or function of neurons throughout different regions of the brain contributes to many of the characteristics of PWS, including hyperphagia, anxiety, OCD behaviors, sleep disturbances, and temper outbursts. However, it’s very difficult to develop effective therapeutics without first understanding which of the various types of brain neurons are specifically involved […]

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From discovery to therapeutic…learning about the FDA process

Knowlege is empowering! For those who are interested in learning more about the drug discovery and approval process, the FDA (Federal Drug Administration) has a new informational website directed specifically at patient education and involvement.

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Potential PWS Treatments Currently in Development

Approach How it works Development Phase Investigators /Company *= FPWR funded Advantages Potential Limitations Genetic Therapies– These therapies seek to activate the PWS region genes on the silent maternal chromosome 15 OR provide critical missing genes OR provide...

July 31, 2015 read more

The Oxytocin Landscape

The science of oxytocin (OT) and its potential therapeutic benefit in PWS continues to be a high profile, priority research area for the PWS community and for FPWR. Several studies have taken place investigating oxytocin as a therapeutic for...

July 31, 2015 read more