Unraveling the mechanisms of cholinergic neuronal impairment in individuals with Prader-Willi Syndrome
Funded Year: 2025This project aims to clarify the role of the brain’s cholinergic system in PWS and its connection to cognitive difficulties and hyperphagia. Dr. Yi and her team hypothesize that acetylecholine (ACh) deficiency in the brains of individuals with PWS may contribute to their cognitive impairments and appetite-related challenges, as the cholinergic...