Home > Request for Applications

The Foundation for Prader-Willi Research (FPWR), a nonprofit organization dedicated to supporting research to advance the understanding and treatment of Prader-Willi syndrome (PWS), announces the availability of funds to support innovative research relevant to PWS.  FPWR is particularly interested in supporting projects that will lead to new treatments to alleviate the symptoms associated with PWS.

Priority will be given to the following areas of research, although alternative areas of high scientific merit will also be considered:

  • Molecular basis of the PWS phenotype; molecular therapeutics
  • Regulation of appetite and energy homeostasis in individuals with PWS; development and evaluation of therapies to regulate appetite and satiety in PWS
  • Etiology of medical, behavioral and psychiatric complications in PWS; development and evaluation of therapeutic interventions
  • Understanding pyschopathalogy in PWS; development and evaluation of interventions

A more complete list of research priorities may be found here.

Funds Available:  Applicants may request up to $100,000 USD in direct costs for the initial year of support, with the possibility of a second year of funding upon competitive renewal.  Indirect costs of up to 8% are allowed.

Eligibility:  Principal Investigators must have a primary faculty appointment at the level of Instructor or higher.  This grant program will be useful for junior faculty in the early stages of their careers, established investigators in other areas of research who wish to enter the field of PWS research, or investigators in the PWS field who are seeking funding to support pilot studies in a new area of PWS research. FPWR seeks to support innovative, high-risk/high reward research.

Application Review and Award: Letters of intent (LOI) will be reviewed for innovation and potential impact, merit and relevance to the mission of FPWR.  Selected LOIs will be invited to submit a full grant proposal.

Full grant proposals meeting the technical requirements will be reviewed on the basis of merit by scientific reviewers with expertise in the research area.  An advocate reviewer will evaluate the relevance of the proposed research to the PWS community.  Final funding decisions will be based on scientific merit, relevance and the suitability of the research with respect to the programmatic goals of FPWR.

Application Guidelines: All LOIs and applications are to be submitted on-line through ProposalCentral (https://proposalcentral.altum.com/). The LOI is limited to a 2-page description. Full grant proposals are limited to a 5-page research plan. Guidelines, review considerations, a list of currently funded projects, can all be found through the links below.


Scientific and advocate review considerations

Previously funded projects

Letter of Intent Due Date:              March 1st, 2016, 5pm EST

Full Proposal Due Date:                 May 9th, 2016, 5pm EST

Please direct questions to: jessica.bohonowych@fpwr.org