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Foundation for Prader-Willi Blog | Research (45)

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Linking Learning with Neurodevelopmental Functioning - Final Report

This project was funded by the Foundation for Prader Willi Research in 2006 and conducted by Drs. Gregory Olley and Anne Wheeler and their team at the University of North Carolina, Chapel Hill (UNC), Center for Development and Learning. Dr. Wheeler i...
May 6, 2009 Read More

Topics: Research

Growth Hormone Therapy Does Not Worsen Scoliosis

The incidence of scoliosis in Prader-Willi syndrome is quite high (~30% in children under the age 10; up to ~80% in kids over the age of 10, compared to <3% in the general population). Because moderate to severe scoliosis can be associated with si...
April 7, 2009 Read More

Topics: Research

Adrenal Insufficiency and PWS

Several recent studies have begun to look more carefully at the causes of death in PWS, particularly in cases where death was sudden and/or unexpected. A review of 64 cases of death in children with PWS noted a high occurrence of respiratory infectio...
April 2, 2008 Read More

Topics: Research

Peptide YY and Obesity: A Promising New Examination

Obese individuals often have a deficiency in peptide YY (PYY), a hormone that is produced by endocrine "L" cells of the lower gastrointestinal tract, the stomach and the brainstem. Low levels of PYY may be a predisposing factor to the development of ...
March 23, 2008 Read More

Topics: Research

Brain-Derived Neurotrophic Factor; Its Role in Obesity

This is a reprint from The Gathered View, courtesy of PWSA (USA). Obesity and problems with overeating can be influenced by a number of factors in the brain. One such factor is brain-derived neurotrophic factor (BDNF), which is involved in eating and...
March 23, 2008 Read More

Topics: Research

An Obsessive Compulsive Mouse

Obsessive-Compulsive Disorder (OCD) affects about 2% of the population. It is characterized by persistent intrusive thoughts (obsessions), repetitive actions (compulsions), and excessive anxiety. As anyone who know someone with PWS can appreciate, OC...
February 9, 2008 Read More

Topics: Research

What's new with ghrelin??

Since its first description in 1999 by Kojima and co-workers, ghrelin has been the subject of intense interest in the scientific community, as evidenced by the more than 2,500 published papers to date. This is good news for those with PWS, who have a...
January 17, 2008 Read More

Topics: Research

Sibutramine evaluated in PWS

Individuals with PWS are, in many ways, perfect subjects for studying the effectiveness of candidate obesity drugs. Excessive weight gain is a common and critical issue, frequently leading to a multitude of medical complications.
December 12, 2007 Read More

Topics: Research

FTO - a new gene influencing obesity

A new article sheds a little bit of light on the latest player in obesity: the FTO gene (the fat-mass and obesity-associated gene). FTO was implicated as a gene important in determining who is more likely to be obese and at risk for diabetes in two g...
December 11, 2007 Read More

Topics: Research

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The Foundation for Prader-Willi Research (federal tax id 31-1763110) is a nonprofit corporation with federal tax exempt status as a public charity under section 501(c)(3).

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