The International Congress of Neuroendocrinology was held this week at Univ Pittsburgh- some very interesting things were dicussed there .They have some nice summaries, including 'lay summaries' of research on hormones important in stress, eating, etc. A â€œnewâ€ neuropeptide (neuropeptide S, NPS) is described that looks very interesting; NPS induces wakefulness, stimulates activity and lessens anxiety. The peptide and its receptors are just being characterized with respect to location, function, etc.
Dr. Bloomâ€™s group recently determined that NPS also decreases food intake (at least for the short term). Determining exactly how this peptide mediates its effects will be the next step.
Neuropeptide s stimulates the hypothalamo-pituitary-adrenal axis and inhibits food intake. Smith KL, Patterson M, Dhillo WS, Patel SR, Semjonous NM, Gardiner JV, Ghatei MA, Bloom SR. Endocrinology. 2006 Jul;147(7):3510-8.