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Jessica Bohonowych

Jessica Bohonowych is a graduate of Duke University, and holds a PhD in Pharmacology and Toxicology at the University of California, Davis. Incorporating her research background, knowledge of pharmacology and drug development, and teaching experience, Jessica works with Theresa Strong in managing FPWR’s grant portfolio, communicating research results and breakthroughs to our community, aiding in special projects such as the Clinical Trials Initiative and Molecular Resource Center, and is heading the development of the Global PWS Registry.

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Mental Health Professionals Release 10 PWS Research Recommendations

October 13, 2016

Mental health professionals have published 10 recommendations for Prader-Willi syndrome (PWS) research. These recommendations create urgency for further research and treatments to improve quality of life and increase independence for people with PWS. The recommendations are included below, from the

Social Communication: Its Role In Behavior & Cognitive Development In PWS

August 29, 2016

In social communication, the ability to appropriately recognize and process facial expressions is critical to understanding others' emotional and mental state. People can often "read" emotions on someone's face, including happiness, sadness, fear, surprise and anger. Scientifcally, this is called

Prader Willi Behavioral Issues May Be Tied to Low GABA Levels in Brain

August 2, 2016

Adolescents and adults with PWS often struggle with temper outbursts, compulsive behaviors, and self-injurious behaviors such as skin-picking. These behavioral challenges impact the quality of life for those with PWS and for their families and caregivers. There are a number

Another piece to the hyperphagia puzzle, loss of POMC neurons in PWS is progressive

May 31, 2015

This month's research blog post comes from guest author Igor Pravdivyi, a member of Dr. Rachel Wevrick's research group at the University of Alberta. Children with PWS usually begin to have increased appetite around age 5, with hyperphagia setting in

Brain imaging shows structural differences between the PWS vs. non-PWS brain

March 6, 2015

It is well known that individuals with PWS often exhibit developmental delays and impaired cognition compare to typically developing peers. There is also evidence that those with PWS are at higher risk than the general population for mental health problems

Sleep Apnea In Infants and Children with PWS: Is a Sleep Study On Your "To-Do" List?

July 29, 2014

In a study from The Hospital for Sick Children, the authors recommend that all infants with PWS be screened for sleep disordered breathing (SDB) and receive oxygen treatment as needed. SDB is an area of great concern for the PWS

PWS iPS cells are helping researchers make breakthroughs

May 29, 2014

One of the exciting breakthroughs in PWS research in recent years has been the development of induced pluripotent stem cells or “iPSCs”. Although there is tremendous excitement among the scientific community about iPSCs, many parents, patients, and advocates still have

Are there benefits to testosterone replacement therapy in adult males with PWS?

October 28, 2013

One well established characteristic of PWS is altered development and function of reproductive systems. This can include hypogonadism; under-development of sexual organs, particularly the testes in males; precocious puberty; and infertility. Of these, hypogonadism, or the production of little to

Targeting serotonin for PWS

April 16, 2013

In a recent email correspondence, Dr. Cunningham at the University of Texas Medical Branch thanked FPWR and described the contribution that FPWR grant funds (2010-2011) have had on the work coming out of her laboratory. She writes, "thank you for

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