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FPWR Blog

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Brain-Derived Neurotrophic Factor; Its Role in Obesity

This is a reprint from The Gathered View, courtesy of PWSA (USA). Obesity and problems with overeating can be influenced by a number of factors in the brain. One such factor is brain-derived neurotrophic factor (BDNF), which is involved in eating and...
March 23, 2008 Read More

Topics: Research

An Obsessive Compulsive Mouse

Obsessive-Compulsive Disorder (OCD) affects about 2% of the population. It is characterized by persistent intrusive thoughts (obsessions), repetitive actions (compulsions), and excessive anxiety. As anyone who know someone with PWS can appreciate, OC...
February 9, 2008 Read More

Topics: Research

What's new with ghrelin??

Since its first description in 1999 by Kojima and co-workers, ghrelin has been the subject of intense interest in the scientific community, as evidenced by the more than 2,500 published papers to date. This is good news for those with PWS, who have a...
January 17, 2008 Read More

Topics: Research

Sibutramine evaluated in PWS

Individuals with PWS are, in many ways, perfect subjects for studying the effectiveness of candidate obesity drugs. Excessive weight gain is a common and critical issue, frequently leading to a multitude of medical complications.
December 12, 2007 Read More

Topics: Research

FTO - a new gene influencing obesity

A new article sheds a little bit of light on the latest player in obesity: the FTO gene (the fat-mass and obesity-associated gene). FTO was implicated as a gene important in determining who is more likely to be obese and at risk for diabetes in two g...
December 11, 2007 Read More

Topics: Research

Abstracts from the 6th International IPWSO Conference

The 6th Annual International Prader-Willi Syndrome Organization (IPWSO) Conference was held in Romania in June 2007. The research abstracts from the conference are available online at the Asociacin Madrile para el SÃndrome de Prader-Willi (AMSPW) web...
August 27, 2007 Read More

Topics: Research

Fat Fish

Zebrafish are hot - these little fish are all the rage in the research world these days. They develop very quickly (embryo to fish in just a couple of days) and scientists are developing better ways to manipulate their genes and use them to study hum...
July 3, 2007 Read More

Topics: Research

Mice show the way to fix genetic disorders (updated)

It's not often that words such as "rescue of neurological deficits", "therapy for cognitive impairment" and "reversal of neurological defects" are used in the titles of papers studying genetic disorders like Angelman, Down, and Rett syndromes, but a ...
May 10, 2007 Read More

Topics: Research

Psychiatric illness in adults with PWS

One of the most troubling features of PWS is the high risk of mental illness in adults with the syndrome. Although a considerable amount has been written on obsessive-compulsive traits, stubbornness and maladaptive behaviors associated with PWS, less...
February 5, 2007 Read More

Topics: Research

About FPWR

The Foundation for Prader-Willi Research (federal tax id 31-1763110) is a nonprofit corporation with federal tax exempt status as a public charity under section 501(c)(3).

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The mission of FPWR is to eliminate the challenges of Prader-Willi syndrome through the advancement of research and therapeutic development.

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