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FPWR Blog

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Why is leptin ignored in obese people and animals?

As many of you know, leptin is the signal released from fat cells that relays a message to the brain that the fat cells are 'full' and it's time to stop eating. It has also been discovered that leptin works directly on the fat cells themselves, decre...
January 8, 2006 Read More

Topics: Research

Mighty muscles

Myostatin normally keeps muscles from growing. Scientist are trying to inhibit myostatin as a therapeutic approach for kids with muscular dystrophy; this strategy has just entered clinical trials using an antibody that sops up the myostatin.
December 13, 2005 Read More

Topics: Research

Clinical trial - modafinil in ADHD

Here is a new study just out in the journal Pediatrics using the new formulation of modafinil for ADHD in children (age 6-17) (a formulation for which Cephalon is seeking FDA approval in children). Modafinil is a "wake promoting" drug that is thought...
December 7, 2005 Read More

Topics: Research

Brain imaging and autism

Brain imaging is really starting to come into its own these days --- the technology is improving and scientists are getting better at interpreting the results. In addition, the NIH is emphasizing support of imagining technology, so hopefully the fiel...
December 7, 2005 Read More

Topics: Research

Narrowing down the genetic region responsible for PWS

Below you'll find the abstract for a newly published paper trying to narrow down exactly which DNA sequences in the PW region of chromosome 15 are responsible for PWS.
December 1, 2005 Read More

Topics: Research

Resource: peer review process

Sense about Science is a UK nonprofit that promotes evidence-based science and public education/discussion regarding the scientific process.
November 25, 2005 Read More

Topics: Research

Genetic characterization of PWS mouse - FPWR supported

Dr. Rob Nicholls has just published another study supported by FPWR. You may recall that his group developed a mouse model of PWS (and Angelman's syndrome if inherited maternally) some years back. We are currently supporting his studies to better cha...
November 16, 2005 Read More

Topics: Research

Imaging 'fullness' in the brain

Another new article is just out on brain imaging during eating in people with PWS, and it better defines the changes in the brain associated with feeling full after a meal. The brain images show the lack of those changes in most people with PWS, even...
November 11, 2005 Read More

Refining the genetic region critical for PWS

Below is a link to recently published paper from Dr. Francke's group at Stanford Univ. You might recall that Dr. Francke received an FPWR grant in the first funding cycle (2003), and the work in this publication was supported by those funds.
August 20, 2005 Read More

Topics: Research

About FPWR

The Foundation for Prader-Willi Research (federal tax id 31-1763110) is a nonprofit corporation with federal tax exempt status as a public charity under section 501(c)(3).

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The mission of FPWR is to eliminate the challenges of Prader-Willi syndrome through the advancement of research and therapeutic development.

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