Foundation for Prader-Willi Blog

Targeted Reactivation of Silenced PWS Genes as a Potential Therapy

All individuals with Prader-Willi syndrome (PWS) have at least one copy of the PWS region from their mother, but it is turned off through a normal biological process called genomic imprinting. Normally, the chromosome 15 that is inherited from the fa...

June 7, 2017 Read More

Topics: Research

Study Explores How and Why of PWS Severity, Mosaicism In PWS By UPD

Individuals with PWS present with a very broad range of severity of symptoms, which is why people often refer to PWS as a “spectrum" disorder. A new study funded by FPWR will help us understand how and why there are different degrees of PWS severity,...

May 31, 2017 Read More

Topics: Research

Study Uses Eye Tracking To Develop Biomarkers for Hyperphagia in PWS

Although hyperphagia (excessive appetite) is a hallmark of PWS, it's one of the most difficult features to accurately measure and characterize. Currently, the main tools in this area are questionnaires about food behavior and food interest. These can...

May 24, 2017 Read More

Topics: Research

Dr. Yossi Tam Searching for Biological Basis of Osteoporosis in PWS

Individuals with PWS are at higher risk for osteoporosis than the general population. Osteoporosis is due to low bone mineral density and leads to weakened bone strength and increased risk for fractures. Dr. Yossi Tam at the Hebrew University of Jeru...

May 17, 2017 Read More

Topics: Research

2017 PWS Research Grants Cover Behavior, Genetics, Hyperphagia & More

We're thrilled to announce our first round of PWS research grants for 2017! Seven outstanding projects were selected for funding, totaling $795,221 in support. These projects address a variety of topics important in PWS, including behavior, genetics,...

May 10, 2017 Read More

Topics: Research

Dr. Ingrid Tein Studies Potential Benefits of CoQ10 in PWS

Many parents of individuals with Prader-Willi syndrome (PWS) have been faced with ambiguous information about the dietary supplement coenzyme Q10 (CoQ10). There are plenty of anecdotal reports of supplemental CoQ10 providing a great improvement in me...

May 3, 2017 Read More

Topics: Research

Biomarkers and Beyond: 2016 Update from PWS Clinical Trials Consortium

Over the past several years, the PWS community has been fortunate to see several potential therapies for PWS enter clinical trials. To date, the only FDA-approved drug for the treatment of PWS is growth hormone, but it's clear that new medications ar...

April 27, 2017 Read More

Topics: Research

Want to Make Friends? New Online Groups Build Social Skills in PWS

A special contribution by guest blogger Elizabeth Roof Elizabeth Roof is a Senior Research Specialist at the Vanderbilt Kennedy Center and directs six research programs with children and adults with rare genetic disorders including Prader-Willi syndr...

April 19, 2017 Read More

Topics: Research

LaSalle Gene Research Paves Way for PWS Sleep and Metabolism Therapies

Sleep disorders are common in Prader-Willi syndrome (PWS). These are associated with central and obstructive apnea, disrupted sleep, and excessive daytime sleepiness. But why exactly do individuals with PWS have abnormal sleep patterns? Dr. Janine La...

April 14, 2017 Read More

Topics: Research

Foundation for Prader-Willi Blog | Research (30)

Categories

Targeted Reactivation of Silenced PWS Genes as a Potential Therapy

Study Explores How and Why of PWS Severity, Mosaicism In PWS By UPD

Study Uses Eye Tracking To Develop Biomarkers for Hyperphagia in PWS

Dr. Yossi Tam Searching for Biological Basis of Osteoporosis in PWS

2017 PWS Research Grants Cover Behavior, Genetics, Hyperphagia & More

Dr. Ingrid Tein Studies Potential Benefits of CoQ10 in PWS

Biomarkers and Beyond: 2016 Update from PWS Clinical Trials Consortium

Want to Make Friends? New Online Groups Build Social Skills in PWS

LaSalle Gene Research Paves Way for PWS Sleep and Metabolism Therapies

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