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Research (21)

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Tony Holland, Leader In PWS Research on Obesity, Satiety, and Behavior

June 14, 2017

There has been much recent interest in the Prader-Willi syndrome (PWS) community regarding vagus nerve stimulation, a novel approach to treat PWS behavior issues, which is being led by Dr. Tony Holland and supported by FPWR. In fact, Dr. Holland,

Dr. Rudolph Leibel: Searching for PWS Causes at Molecular Level In Brain

June 8, 2017

Many may remember Dr. Rudolph Leibel’s presentation on stem cells and Prader-Willi Syndrome (PWS) at the FPWR Research Conference in November 2014. He also published a breakthrough discovery in the Journal of Clinical Investigation, with Lisa Burnett, PhD, suggesting that

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Targeted Reactivation of Silenced PWS Genes as a Potential Therapy

June 7, 2017

All individuals with Prader-Willi syndrome (PWS) have at least one copy of the PWS region from their mother, but it is turned off through a normal biological process called genomic imprinting. Normally, the chromosome 15 that is inherited from the

Study Explores How and Why of PWS Severity, Mosaicism In PWS By UPD

May 31, 2017

Individuals with PWS present with a very broad range of severity of symptoms, which is why people often refer to PWS as a “spectrum" disorder. A new study funded by FPWR will help us understand how and why there are

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Dr. Ingrid Tein Studies Potential Benefits of CoQ10 in PWS

May 3, 2017

Many parents of individuals with Prader-Willi syndrome (PWS) have been faced with ambiguous information about the dietary supplement coenzyme Q10 (CoQ10). There are plenty of anecdotal reports of supplemental CoQ10 providing a great improvement in metabolic function and energy levels,

Biomarkers and Beyond: 2016 Update from PWS Clinical Trials Consortium

April 27, 2017

Over the past several years, the PWS community has been fortunate to see several potential therapies for PWS enter clinical trials. To date, the only FDA-approved drug for the treatment of PWS is growth hormone, but it's clear that new

LaSalle Gene Research Paves Way for PWS Sleep and Metabolism Therapies

April 14, 2017

Sleep disorders are common in Prader-Willi syndrome (PWS). These are associated with central and obstructive apnea, disrupted sleep, and excessive daytime sleepiness. But why exactly do individuals with PWS have abnormal sleep patterns? Dr. Janine LaSalle has uncovered an exciting

New Evidence Supports Benefits of Hippotherapy

April 12, 2017

A new study highlighted in Medical News Today further supports the benefits of hippotherapy with regards to behavioral tasks and cognitive development. Hippotherapy is the use of horseback riding as a therapeutic or rehabilitative treatment. The full article is available

Bearden Research Transforming Understanding of Mental Illness in PWS

April 7, 2017

Behavior and mental health issues are an important part of Prader-Willi syndrome (PWS). In particular, one of the most challenging aspects for families to face is the onset of psychosis (i.e., mental illness characterized by symptoms, such as delusions or

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