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Research (20)

Endocannabinoids As a Potential Therapy for Hyperphagia in PWS

August 16, 2017

The mechanisms in the nervous system that control appetite and satiation are complex. And the dysfunctions in those mechanisms that lead to hyperphagia and obesity in people with PWS are likewise complex and unclear. Yet, several hypothalamic appetite regulators have

Orthopedic Issues and Prader-Willi Syndrome: Q&A With Dr. van Bosse

August 14, 2017

Like many medical providers, Dr. Harold van Bosse came to specialize on Prader-Willi Syndrome (PWS) by happenstance. In the late 90s, a pediatric patient with PWS came under his care for treatment of scoliosis. At the time, not much was

Studies Show PWS Caregiver Stress Can And Should Be Addressed

August 9, 2017

Parenting a child with special needs can be full of wonderful unexpected moments of joy such as seeing your child accomplish a difficult task or witnessing him or her make progress in therapies after months of hard work. These are

Feeding Challenges and PWS: Q&A With Speech Pathologist Sara Parker

August 8, 2017

Food, hunger, mealtimes, eating — these are all important issues for people with PWS and their families. Sara Parker knows all about feeding challenges and PWS. She's a speech pathologist who specializes in pediatric feeding and has spent more than

Hougland On PWS Research: The Right People Asking The Right Questions

August 3, 2017

Dr. James Hougland is a multi-award–winning biochemist at Syracuse University and recipient of a 2013 BIG Grant through the Foundation for Prader-Willi Research. FPWR funded his study on ghrelin O-acyltransferase (GOAT), an enzyme that modifies ghrelin. We reached out to

Accelerating the Development of Treatments for PWS

July 26, 2017

While genetic therapy has the potential to be transformative for Prader-Willi syndrome, the fact is genetic therapy technology is still in its early stages and it could be many years before it’s viable for PWS. While FPWR continues to move

Reiter Studies PWS Genetics With Dental Pulp Stem Cells

July 6, 2017

You may have seen requests for parents to donate the lost baby teeth of their children with PWS for research. What can these baby teeth do for Prader-Willi research? The answer is that Dr. Lawrence Reiter has implemented a novel

Incidence of Autism In People With PWS Lower Than Previously Thought

July 5, 2017

The potential overlap between PWS and symptoms of autism spectrum disorder (ASD) has been the subject of discussion and research for some time now. In the past, research found estimates of autism in people with PWS to be as high

Dr. Hof Looks for Link Between Brain Neurons and Mental Health in PWS

June 21, 2017

Cognition, social behavior, and decision-making are common challenges among individuals with PWS. The brain region that controls many of these functions is called the frontal lobe. To date, there has been little work on understanding differences in this part of

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