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Research (19)

Feeding Challenges and PWS: Q&A With Speech Pathologist Sara Parker

August 8, 2017

Food, hunger, mealtimes, eating — these are all important issues for people with PWS and their families. Sara Parker knows all about feeding challenges and PWS. She's a speech pathologist who specializes in pediatric feeding and has spent more than

Hougland On PWS Research: The Right People Asking The Right Questions

August 3, 2017

Dr. James Hougland is a multi-award–winning biochemist at Syracuse University and recipient of a 2013 BIG Grant through the Foundation for Prader-Willi Research. FPWR funded his study on ghrelin O-acyltransferase (GOAT), an enzyme that modifies ghrelin. We reached out to

Accelerating the Development of Treatments for PWS

July 26, 2017

While genetic therapy has the potential to be transformative for Prader-Willi syndrome, the fact is genetic therapy technology is still in its early stages and it could be many years before it’s viable for PWS. While FPWR continues to move

Reiter Studies PWS Genetics With Dental Pulp Stem Cells

July 6, 2017

You may have seen requests for parents to donate the lost baby teeth of their children with PWS for research. What can these baby teeth do for Prader-Willi research? The answer is that Dr. Lawrence Reiter has implemented a novel

Incidence of Autism In People With PWS Lower Than Previously Thought

July 5, 2017

The potential overlap between PWS and symptoms of autism spectrum disorder (ASD) has been the subject of discussion and research for some time now. In the past, research found estimates of autism in people with PWS to be as high

Dr. Hof Looks for Link Between Brain Neurons and Mental Health in PWS

June 21, 2017

Cognition, social behavior, and decision-making are common challenges among individuals with PWS. The brain region that controls many of these functions is called the frontal lobe. To date, there has been little work on understanding differences in this part of

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Tony Holland, Leader In PWS Research on Obesity, Satiety, and Behavior

June 14, 2017

There has been much interest in the Prader-Willi syndrome (PWS) community regarding vagus nerve stimulation, a novel approach to treat challenging PWS-related behaviors. Research into vagus nerve stimulation (VNS) firstwhich is being led by Dr. Tony Holland and supported by

Dr. Rudolph Leibel: Searching for PWS Causes at Molecular Level In Brain

June 8, 2017

Many may remember Dr. Rudolph Leibel’s presentation on stem cells and Prader-Willi Syndrome (PWS) at the FPWR Research Conference in November 2014. He also published a breakthrough discovery in the Journal of Clinical Investigation, with Lisa Burnett, PhD, suggesting that

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Targeted Reactivation of Silenced PWS Genes as a Potential Therapy

June 7, 2017

All individuals with Prader-Willi syndrome (PWS) have at least one copy of the PWS region from their mother, but it is turned off through a normal biological process called genomic imprinting. Normally, the chromosome 15 that is inherited from the

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