Impact of carbohydrate restricted diet upon growth and hyperphagia/food anxiety in children with Prader-Willi syndrome

Prader-Willi syndrome is a disorder of genetic imprinting characterized by common features including early feeding problems and failure to thrive followed by gradual weight gain and development of hyperphagia. Long-term practice has recommended use of dietary restriction using a variety of approaches for weight control/obesity prevention of obesity with some recent anecdotal data suggesting benefits of carbohydrate restricted diets upon hyperphagia/anxiety. A pilot study of implementation of a modified Atkins diet in school aged children with Prader-Willi syndrome is proposed to assess the impact upon behavior and hyperphagia.


*Funded by FPWR-Canada

Research Outcomes: Publications

The modified Atkins diet in children with Prader-Willi syndrome. Felix G, Kossoff E, Barron B, Krekel C, Getzoff Testa E, Scheimann A.  Orphanet Journal of Rare Diseases (2020) 15:135. doi: 10.1186/s13023-020-01412-w.

Funded Year:


Awarded to:

Ann Scheimann, MD




Johns Hopkins University


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